Research Focus in the Ogawa Lab

Our main research focus, in the “Laboratory of Behavioral Neuroendocrinology”, is to study neuroendocrine bases of various behaviors, such as emotional, socio-sexual, and affiliative behavior in relation to establishment of social bonding. Through active collaborative studies at molecular, neuroanatomical, neurophysiological, psychological and clinical levels, we have been investigating how these behaviors are regulated by time-specific, sex-specific and site-specific hormonal action in the brain. Particularly, using a number of gene manipulation methods, including transgenic and knockout mouse models, we have been identifying molecular and neural mechanisms of estrogenic regulation of emotional and social behavior. We also have been investigating how environmental and experiential factors (e.g. early life condition) may affect development of these behaviors. Our laboratory, as the only behavioral neuroendocrinology lab and one of the best biopsychology labs in Japan, is well equipped for behavioral, neuroanatomical and neuroendocrine studies. A dozen of post-doctoral, graduate, and undergraduate students are currently studying “behavior” from various points of view. Our ultimate goal is to provide neurobiological evidence for better understanding of various problems associated with social deficits and lack of social relationships, and establish a research field for biology-based translational social neuroscience, ie., social behavioral neuroendocrinology.

Attached File: Research in Ogawa Lab.pdf

Category : About Us / Research Theme

Invited Lecture at the 11th IBRO Associate School of Neuroscience


Ogawa, S.
Role of Estrogen-Induced Gene Expression in the Regulation of Socio-Sexual and Emotional Behavior: Studies with Knockout Mice and Brain Site-Specific Gene Knockdown by RNAi Method.
In the 11th IBRO Associate School of Neuroscience, December 3-7, 2007, Monash University, Sunway Campus, Kuala Lumpur, Malaysia.

Attached File: Ogawa Abstract IBRO.pdf

Category : Lab Topics

Molecular Mechanisms of Sex Differentiation Newsletter


Progress report of the Ogawa Lab for the studies supported by KAKENHI program "Molecular Mechanisms of Sex Differentiation".

Attached File: MMSD 2007.pdf

Category : Lab Topics

KOKORO Seminar #14


MEXT: Initiatives for Attractive Education in Graduate Schools
International Program for New Frontiers in ‘Mind and Brain’ Science
14th KOKORO Seminar

September 21, 2007, 18:00~19:00
Research Building D, Multi-Media Room

Title:Neurobehavioural and Molecular Changes Induced by Methylmercury Exposure during Development.
Speaker:Dr. Sandra Ceccatelli
Affiliation:Karolinska Institute

Category : Seminars by Invited Speakers

KOKORO Seminar #13


MEXT: Initiatives for Attractive Education in Graduate Schools
International Program for New Frontiers in ‘Mind and Brain’ Science
13th KOKORO Seminar

September 18, 2007, 18:00~19:00
Research Building D, Lecture Hall

Title:"いやされない傷:児童虐待と傷ついていく脳" (Talk in Japanese)
Speaker:Dr. Akemi Tomoda
Affiliation:Graduate School of Medical Sciences, Kumamoto University

Category : Seminars by Invited Speakers